Lixtraxen Injection and Mexitil
Determining the interaction of Lixtraxen Injection and Mexitil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using lidocaine together with mexiletine may increase the effects of lidocaine. This can cause increased side effects or cause your condition to change. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Mexiletine may increase the serum lidocaine levels and toxicity. The mechanism is unknown.
MANAGEMENT: Management consists of monitoring the patient for symptoms of neurotoxicity, monitoring plasma levels and decreasing the lidocaine dosage if an interaction is suspected.
- Christie JM, Valdes C, Markowsky SJ "Neurotoxicity of lidocaine combined with mexiletine." Anesth Analg 77 (1993): 1291-4
- Geraets DR, Scott SD, Ballew KA "Toxicity potential of oral lidocaine in a patient receiving mexiletine." Ann Pharmacother 26 (1992): 1380-1
Generic Name: epinephrine / lidocaine
Brand name: D-Care 100X, Lignospan Forte, Lignospan Standard, Xylocaine MPF With Epinephrine, Xylocaine With Epinephrine
Synonyms: Lidocaine and Epinephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lixtraxen Injection-MG 217 Topical
- Lixtraxen Injection-MG Plus Protein
- Lixtraxen Injection-MG217 Medicated Tar
- Lixtraxen Injection-Mg217 Sal-Acid Topical
- Lixtraxen Injection-Mi-Acid
- Lixtraxen Injection-Mi-Acid Double Strength
- Mexitil-LMD
- Mexitil-LMD Injection
- Mexitil-LMX 4 Topical application
- Mexitil-LMX 5
- Mexitil-LMX 5 Topical application
- Mexitil-Lo Loestrin Fe