LMD Injection and Vitrase injection

• Generic Name: dextran, low molecular weight
• Dosage Forms: injection, solution
• Other Brand Names: LMD

Early fluid replacement and plasma volume expansion in the adjunctive treatment of certain types of shock or impending shock (e.g., burns, surgery, hemorrhage, or other trauma in which a circulating volume deficit is present) when whole blood or blood products are not available, or when the need for haste precludes the necessary cross-matching of blood.

Minimizes sludging of blood as a result of microcirculation effects.

Not a replacement for other forms of therapy; complementary to fluids and electrolytes.

Priming fluid (alone or as an additive to other priming fluids) in pump oxygenators for perfusion during extracorporeal circulation.

Prophylaxis of venous thrombosis and pulmonary embolism for surgical procedures associated with a high risk of thromboembolic complications (e.g., hip surgery).

May be beneficial in patients undergoing hip surgery; however, has not been shown to be more effective than oral anticoagulants or heparin in patients undergoing general surgery.

The American College of Chest Physicians (ACCP) does not recommend as sole method of thromboprophylaxis in elective hip arthroplasty.

• Generic Name: hyaluronidase
• Dosage Forms: injection, solution
• Other Brand Names: Amphadase, Hylenex, Vitrase, Wydase, Hydase

Hyaluronidase is a genetically designed protein.

Hyaluronidase is used together with fluids injected into the body to treat dehydration. Hyaluronidase can also be used as an aid in helping your body absorb other injected medications.

Hyaluronidase is also used to help contrast dyes in your body show more clearly on certain types of x-rays or scans.

Hyaluronidase may also be used for purposes not listed in this medication guide.