Lomitapide Mesylate and Panretin

• Generic Name: lomitapide
• Dosage Forms: n.a.
• Other Brand Names: Juxtapid

Adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available, to reduce LDL-cholesterol, total cholesterol, apolipoprotein B (apo B), and non-HDL-cholesterol concentrations in the management of homozygous familial hypercholesterolemia (designated an orphan drug by US FDA for use in this condition).

Safety and efficacy not established in patients with hypercholesterolemia who do not have homozygous familial hypercholesterolemia.

Effects on cardiovascular morbidity and mortality not established.

• Generic Name: alitretinoin topical
• Dosage Forms: gel
• Other Brand Names: Panretin

Alitretinoin is a retinoid, related to vitamin A. Alitretinoin affects the growth and development of skin cells.

Panretin (for the skin) is used to treat skin lesions caused by AIDS-related Kaposi's sarcoma.

Panretin may also be used for purposes not listed in this medication guide.