Lomitapide Mesylate and Quinidex Extentabs

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Lomitapide may increase the blood levels and effects of quiNIDine. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration with lomitapide may increase the plasma concentrations of drugs that are substrates of P-glycoprotein. The proposed mechanism is decreased clearance in the intestine and/or liver due to inhibition of P-glycoprotein-mediated drug efflux by lomitapide.

MANAGEMENT: Caution is advised if lomitapide must be used concurrently with medications that are substrates of the P-glycoprotein efflux transporter, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever lomitapide is added to or withdrawn from therapy.

Lomitapide Mesylate

Generic Name: lomitapide

Brand name: Juxtapid

Synonyms: Lomitapide

What is Lomitapide Mesylate?

Quinidex Extentabs

Generic Name: quinidine

Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release

Synonyms: n.a.

What is Quinidex Extentabs?