Lomotil (Diphenoxylate and Atropine Solution) and Sodium Bicarbonate Infant Injection
Determining the interaction of Lomotil (Diphenoxylate and Atropine Solution) and Sodium Bicarbonate Infant Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using atropine together with sodium bicarbonate can decrease the effects of atropine. Sodium bicarbonate should be separated from oral atropine by 3 to 4 hours. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Concurrent administration of antacids or adsorbent antidiarrheal agents may decrease the oral bioavailability of atropine.
MANAGEMENT: Doses of antacids or adsorbent antidiarrheals should be separated from oral atropine by 3 to 4 hours.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: atropine / diphenoxylate
Brand name: Lomotil, Lonox, Lomocot, Vi-Atro
Synonyms: Lomotil
Generic Name: sodium bicarbonate
Brand name: Neut
Synonyms: Sodium bicarbonate, Sodium Bicarbonate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lomotil (Diphenoxylate and Atropine Solution)-Sodium Bicarbonate Injection
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