Lomotil (Diphenoxylate and Atropine Solution) and SymlinPen 60
Determining the interaction of Lomotil (Diphenoxylate and Atropine Solution) and SymlinPen 60 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using atropine together with pramlintide. Due to its effect on stomach emptying, pramlintide should not be used in patients taking atropine. Atropine may also slow stomach emptying or slow the intestinal absorption of nutrients. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The use of pramlintide in combination with drugs that alter gastrointestinal motility (e.g., loperamide; anticholinergic agents) or drugs that slow the intestinal absorption of nutrients (e.g., alpha-glucosidase inhibitors) has not been studied. Because pramlintide slows gastric emptying, the potential for a pharmacodynamic interaction is possible.
MANAGEMENT: Due to its effect on gastric emptying, pramlintide therapy should not be considered for patients taking drugs that alter gastrointestinal motility or drugs that slow the intestinal absorption of nutrients.
- "Product Information. Symlin (pramlintide)." Amphastar Pharmaceuticals Inc, South El Monte, CA.
Generic Name: atropine / diphenoxylate
Brand name: Lomotil, Lonox, Lomocot, Vi-Atro
Synonyms: Lomotil
Generic Name: pramlintide
Brand name: SymlinPen 120, SymlinPen 60, Symlin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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