Lopinavir and ritonavir and Perampanel Oral Suspension
Determining the interaction of Lopinavir and ritonavir and Perampanel Oral Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with potent inhibitors of CYP450 3A4 may increase the plasma concentrations of perampanel, which is primarily metabolized by the isoenzyme. In a clinical study, ketoconazole 400 mg daily for 10 days resulted in an increase in perampanel AUC by 20% and half-life by 15%. The clinical significance is unknown.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
Generic Name: lopinavir / ritonavir
Brand name: Kaletra
Synonyms: Lopinavir and Ritonavir
Generic Name: perampanel
Brand name: Fycompa
Synonyms: Perampanel
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lopinavir and ritonavir-Perampanel Tablets
- Lopinavir and ritonavir-Peranex HC
- Lopinavir and ritonavir-Percocet
- Lopinavir and ritonavir-Percocet 10/325
- Lopinavir and ritonavir-Percocet 2.5/325
- Lopinavir and ritonavir-Percocet 5/325
- Perampanel Oral Suspension-Lopinavir and Ritonavir Oral Solution
- Perampanel Oral Suspension-Lopinavir and Ritonavir Solution
- Perampanel Oral Suspension-Lopinavir and Ritonavir Tablets
- Perampanel Oral Suspension-Lopreeza
- Perampanel Oral Suspension-Lopressor
- Perampanel Oral Suspension-Lopressor (Metoprolol Injection)