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Lopressor (Metoprolol Tablets) and Methacholine

Determining the interaction of Lopressor (Metoprolol Tablets) and Methacholine and the possibility of their joint administration.

Check result:
Lopressor (Metoprolol Tablets) <> Methacholine
Relevance: 08.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using metoprolol and methacholine is not recommended. Taking these drugs together can cause symptoms of chest tightness, difficulity breathing, shortness of breath, or nausea. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Patients who are concurrently receiving beta blockers may have exaggerated or prolonged responses (i.e., bronchoconstriction) to methacholine challenge and may not respond readily to treatment. Beta-2-adrenergic blockade increases airway resistance. Ophthalmically applied beta blockers undergo some systemic absorption and potentially may also interact.

MANAGEMENT: Administration of methacholine to a patient on any beta blocker therapy is considered contraindicated.

References
  • "Product Information. Provocholine (methacholine)." Methapharm Inc, Brantford, ON.
Lopressor (Metoprolol Tablets)

Generic Name: metoprolol

Brand name: Lopressor, Kapspargo Sprinkle, Toprol-XL, Toprol XL

Synonyms: Lopressor (Injection), Lopressor

Methacholine

Generic Name: methacholine

Brand name: Provocholine

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle