Lorbrena and Pemoline

• Generic Name: lorlatinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Lorbrena

Lorbrena (lorlatinib) is prescription medicine used to treat a certain type of non-small cell lung cancer that has spread to other parts of the body.

Lorbrena is used only if your cancer has a specific genetic marker (an abnormal "ALK" gene). Your doctor will test you for this gene.

Lorbrena is given after other cancer treatments did not work or have stopped working.

Lorbrena was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.

• Generic Name: pemoline
• Dosage Forms: n.a.
• Other Brand Names:

Pemoline belongs to the group of medicines called central nervous system (CNS) stimulants. It is used to treat children with attention-deficit hyperactivity disorder (ADHD).

Pemoline increases attention and decreases restlessness in children who are overactive, cannot concentrate for very long or are easily distracted, and are emotionally unstable. Pemoline is used as part of a total treatment program that also includes social, educational, and psychological treatment.

Rarely, pemoline has caused serious liver problems. You and your doctor should talk about the good pemoline will do as well as the risks of using it. In addition, you will be asked to sign an informed consent form stating that you understand and agree to accept the risk of liver problems.

Pemoline is available only with your doctor's prescription.