Lorcaserin Hydrochloride and Orkambi (Lumacaftor and Ivacaftor Granules)

• Generic Name: lorcaserin
• Dosage Forms: n.a.
• Other Brand Names: Belviq, Belviq XR

Adjunct to caloric restriction and increased physical activity in the chronic management of obesity.

Used in patients who are obese (pretreatment body mass index [BMI] ≥30 kg/m2); also used in overweight patients with pretreatment BMI ≥27 kg/m2 in the presence of a weight-related risk factor or disease (e.g., hypertension, type 2 diabetes mellitus, dyslipidemia).

Indicated only for monotherapy; safety and efficacy in combination with other weight loss products (prescription drugs [e.g., phentermine], OTC drugs, herbal preparations) not established.

Long-term effects on cardiovascular morbidity and mortality associated with obesity not established; safety and efficacy beyond 2 years of use not established.

• Generic Name: ivacaftor / lumacaftor
• Dosage Forms: tablet, film coated
• Other Brand Names: Orkambi

• It is used to treat cystic fibrosis.