Lorcaserin Tablets and Sildenafil Citrate
Determining the interaction of Lorcaserin Tablets and Sildenafil Citrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using lorcaserin together with sildenafil. Combining these medications may increase the risk of priapism, which is a prolonged and painful erection unrelated to sexual activity. You should immediately discontinue these medications and seek emergency medical attention if you have an erection lasting longer than 4 hours. If not treated promptly, priapism can cause irreversible damage to the penile tissue. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Theoretical concerns exist that coadministration of lorcaserin and drugs used for the treatment of erectile dysfunction may increase the risk of priapism (painful erections greater than 6 hours in duration). Lorcaserin may cause priapism due to 5-HT2C receptor agonism. If not treated promptly, priapism can result in irreversible damage to the erectile tissue.
MANAGEMENT: There is limited experience with the combination of lorcaserin and medications indicated for erectile dysfunction. Caution is advised if coadministration is necessary, particularly in patients with risk factors for priapism such as sickle cell anemia, multiple myeloma, leukemia, or anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie's disease). Men who have an erection lasting longer than 4 hours, whether painful or not, should immediately discontinue these drugs and seek emergency medical attention.
- "Product Information. Belviq (lorcaserin)." Eisai Inc, Teaneck, NJ.
Generic Name: lorcaserin
Brand name: Belviq, Belviq XR
Synonyms: Lorcaserin
Generic Name: sildenafil
Brand name: Revatio, Viagra
Synonyms: Sildenafil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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