Lorlatinib and Mektovi

• Generic Name: lorlatinib
• Dosage Forms: n.a.
• Other Brand Names: Lorbrena

Lorlatinib is used to treat a certain type of non-small cell lung cancer that has spread to other parts of the body.

Lorlatinib is used only if your cancer has a specific genetic marker (an abnormal "ALK" gene). Your doctor will test you for this gene.

Lorlatinib is given after other cancer treatments did not work or have stopped working.

Lorlatinib was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to lorlatinib, but further studies are needed.

Lorlatinib may also be used for purposes not listed in this medication guide.

• Generic Name: binimetinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Mektovi

Mektovi (binimetinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Mektovi is a prescription medicine used in combination with another medicine called encorafenib (Braftovi) to treat melanoma (skin cancer) in people who have a "BRAF" gene mutation. These medicines are for use in treating melanoma that cannot be treated with surgery or has spread to other parts of the body.

Mektovi may also be used for purposes not listed in this medication guide.