Lortab (Hydrocodone and Acetaminophen Liquid) and Sunmark Acid Reducer Maximum Strength
Determining the interaction of Lortab (Hydrocodone and Acetaminophen Liquid) and Sunmark Acid Reducer Maximum Strength and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / hydrocodone
Brand name: Hycet, Lorcet, Lortab 10/325, Lortab 5/325, Lortab 75/325, Lortab Elixir, Norco, Verdrocet, Vicodin, Xodol, Zamicet, Anexsia, Dolorex Forte, Liquicet, Lortab, Maxidone, Polygesic, Stagesic, Zydone, Zyfrel
Synonyms: Lortab
Generic Name: ranitidine
Brand name: Zantac
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lortab (Hydrocodone and Acetaminophen Liquid)-Sunmark Acid Reducer Ranitidine
- Lortab (Hydrocodone and Acetaminophen Liquid)-Sunmark All Day Allergy-D
- Lortab (Hydrocodone and Acetaminophen Liquid)-Sunmark Anti-Diarrheal
- Lortab (Hydrocodone and Acetaminophen Liquid)-Sunmark Anti-Diarrheal Tablet
- Lortab (Hydrocodone and Acetaminophen Liquid)-SunMark ClearLax
- Lortab (Hydrocodone and Acetaminophen Liquid)-Sunmark Hour Allergy Relief
- Sunmark Acid Reducer Maximum Strength-Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)
- Sunmark Acid Reducer Maximum Strength-Lortab Oral Solution
- Sunmark Acid Reducer Maximum Strength-Lortab Tablets
- Sunmark Acid Reducer Maximum Strength-Lortuss DM
- Sunmark Acid Reducer Maximum Strength-Lortuss EX
- Sunmark Acid Reducer Maximum Strength-Lortuss LQ