Loryna and Safinamide Mesylate

• Generic Name: drospirenone / ethinyl estradiol
• Dosage Forms: tablets
• Other Brand Names: Gianvi, Jasmiel, Loryna, Nikki, Ocella, Syeda, Vestura, Yasmin, Yaz, Zarah, Lo-Zumandimine, Zumandimine, Ocella, Yasmin 28, Yaz

Loryna is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary). Loryna also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Loryna is used as contraception to prevent pregnancy. This medicine is also used to treat moderate acne in women who are at least 14 years old and have started having menstrual periods, and who wish to use birth control pills.

Yaz is also used to treat the symptoms of premenstrual dysphoric disorder (PMDD), such as anxiety, depression, irritability, trouble concentrating, lack of energy, sleep or appetite changes, breast tenderness, joint or muscle pain, headache, and weight gain.

Loryna may also be used for purposes not listed in this medication guide.

• Generic Name: safinamide
• Dosage Forms: n.a.
• Other Brand Names: Xadago

Used as an adjunct to levodopa-carbidopa for the symptomatic treatment of parkinsonian syndrome (e.g., parkinsonism, Parkinson disease [paralysis agitans]) in patients who experience “off” episodes (i.e., time when drug effect wears off and parkinsonian manifestations return).

Shown to be effective only in combination with levodopa-carbidopa; efficacy of safinamide monotherapy not established.