Losec and Nifedical XL
Determining the interaction of Losec and Nifedical XL and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Omeprazole may increase the absorption or interfere with the metabolism of at least one dihydropyridine calcium channel blocker (CCB)--nifedipine. The pharmacologic effect of nifedipine may be enhanced. Although unlikely to be of clinical significance, when omeprazole and a CCB are coadministered, monitoring for CCB toxicity should be considered.
- Andersson T "Omeprazole drug interaction studies." Clin Pharmacokinet 21 (1991): 195-212
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Adalat (nifedipine)." Bayer, West Haven, CT.
Generic Name: omeprazole
Brand name: FIRST Omeprazole, Omeprazole + SyrSpend SF Alka, Prilosec, Prilosec OTC, Zegerid>, Prilosec, Prilosec OTC
Synonyms: Omeprazole
Generic Name: nifedipine
Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat
Synonyms: Nifedical XL (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Losec-Nifedipine
- Losec-Nifedipine Capsules
- Losec-Nifedipine Extended-Release Tablets
- Losec-Niferex
- Losec-Niferex Elixir
- Losec-Night Cast R Topical
- Nifedical XL-Lotemax
- Nifedical XL-Lotemax (Loteprednol Eye Drops 0.5% and 1%)
- Nifedical XL-Lotemax (Loteprednol Eye Gel)
- Nifedical XL-Lotemax (Loteprednol Eye Ointment)
- Nifedical XL-Lotemax Eye Gel
- Nifedical XL-Lotemax Eye Ointment