Loteprednol Etabonate and Paroxetine Hydrochloride

• Generic Name: loteprednol ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Alrex, Inveltys, Lotemax, Lotemax SM

Symptomatic relief of seasonal allergic (hay fever, pollinosis) conjunctivitis.

Symptomatic relief of corticosteroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe (i.e., allergic conjunctivitis, acne rosacea keratitis, superficial punctate keratitis, herpes zoster keratitis, iritis, and cyclitis. Use in conjunction with appropriate anti-infective therapy in some cases of conjunctival infection, when the benefits of reducing edema and inflammation outweigh the risks associated with use of topical corticosteroids.

Loteprednol etabonate 0.5% less effective than prednisolone acetate 1% in the management of anterior uveitis.

Treatment of postoperative ocular inflammation following ocular surgery.

Used in fixed combination with tobramycin in certain bacterial ocular infections.

• Generic Name: paroxetine
• Dosage Forms: n.a.
• Other Brand Names: Brisdelle, Paxil, Paxil CR, Pexeva

Management of major depressive disorder.

Efficacy in hospital settings not established.

Management of OCD; SSRIs reduce but do not completely eliminate obsessions and compulsions.

Management of panic disorder with or without agoraphobia.

Management of social phobia (social anxiety disorder).

Management of generalized anxiety disorder.

Management of PTSD (alone or in combination with psychotherapy).

Management of PMDD.

Has been used for the management of premature ejaculation.

Has been used for the management of diabetic neuropathy.

Has been used for the management of chronic headache.