Loteprednol Etabonate and Pramlintide Acetate

• Generic Name: loteprednol ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Alrex, Inveltys, Lotemax, Lotemax SM

Symptomatic relief of seasonal allergic (hay fever, pollinosis) conjunctivitis.

Symptomatic relief of corticosteroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe (i.e., allergic conjunctivitis, acne rosacea keratitis, superficial punctate keratitis, herpes zoster keratitis, iritis, and cyclitis. Use in conjunction with appropriate anti-infective therapy in some cases of conjunctival infection, when the benefits of reducing edema and inflammation outweigh the risks associated with use of topical corticosteroids.

Loteprednol etabonate 0.5% less effective than prednisolone acetate 1% in the management of anterior uveitis.

Treatment of postoperative ocular inflammation following ocular surgery.

Used in fixed combination with tobramycin in certain bacterial ocular infections.

• Generic Name: pramlintide
• Dosage Forms: n.a.
• Other Brand Names: SymlinPen 120, SymlinPen 60, Symlin

Treatment of type 1 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control on insulin therapy.

Treatment of type 2 diabetes mellitus as an adjunct to preprandial insulin therapy with or without concomitant metformin and/or a sulfonylurea in patients without adequate glycemic control on insulin therapy alone or in combination with metformin and/or a sulfonylurea.

Therapy should only be considered in patients with type 1 or 2 diabetes mellitus who are receiving insulin and have failed to achieve adequate glycemic control despite individualized insulin management. (See Patient Selection under Cautions.)