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Lucentis and Visudyne

Determining the interaction of Lucentis and Visudyne and the possibility of their joint administration.

Check result:
Lucentis <> Visudyne
Relevance: 23.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using verteporfin together with ranibizumab ophthalmic can cause inflammation to the eye. Contact your doctor if your condition worsens or if you develop eye irritation. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The manufacturer reports that when ranibizumab intravitreal injection was used adjunctively with verteporfin photodynamic therapy, 12 of 105 patients (11%) developed serious intraocular inflammation. In 10 of the 12 patients, inflammation occurred when ranibizumab was administered 7 days (+/- 2 days) after verteporfin photodynamic therapy.

MANAGEMENT: Caution is advised if ranibizumab is coadministered with verteporfin photodynamic therapy.

References
  • "Product Information. Lucentis (ranibizumab ophthalmic)." Genentech, South San Francisco, CA.
Lucentis

Generic Name: ranibizumab ophthalmic

Brand name: Lucentis

Synonyms: n.a.

Visudyne

Generic Name: verteporfin

Brand name: Visudyne

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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