Luminal and Topiragen

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

The effect of coadministration of topiramate with either phenobarbital or primidone has not been fully evaluated. The coadministration of topiramate with other antiepileptic drugs, such as phenytoin, valproic acid and carbamazepine has led to alterations in plasma concentrations of one or both drugs. One study has demonstrated that there is less than a 10% change in plasma concentrations of phenobarbital or primidone when coadministered with topiramate. It is expected that topiramate levels would decrease. Use caution if phenobarbital or primidone are coadministered with topiramate, and adjust dosages if needed.

Luminal

Generic Name: phenobarbital

Brand name: Luminal, Solfoton

Synonyms: n.a.

What is Luminal?

Topiragen

Generic Name: topiramate

Brand name: Qudexy XR Sprinkle, Topamax, Topamax Sprinkle, Trokendi XR, Qudexy XR, Topiragen

Synonyms: Topiragen (Oral)

What is Topiragen?