Lurasidone Hydrochloride and Pertuzumab Intravenous

• Generic Name: lurasidone
• Dosage Forms: n.a.
• Other Brand Names: Latuda

Acute treatment of schizophrenia in adults.

American Psychiatric Association (APA) considers most atypical antipsychotic agents first-line drugs for management of the acute phase of schizophrenia (including first psychotic episodes).

Patients who do not respond to or tolerate one drug may be successfully treated with an agent from a different class or with a different adverse effect profile.

Treatment (alone or in combination with lithium or valproate) of major depressive episodes associated with bipolar I disorder (bipolar depression).

Appears less likely to cause weight gain and to adversely affect metabolic parameters than some other atypical antipsychotic agents (e.g., olanzapine, quetiapine). Consider as alternative therapy in patients at higher risk of metabolic abnormalities (e.g., those with diabetes mellitus or hyperlipidemia).

Manufacturer states that efficacy of lurasidone in the treatment of mania associated with bipolar disorder has not been established.

• Generic Name: pertuzumab
• Dosage Forms: n.a.
• Other Brand Names: Perjeta

Pertuzumab injection is used to treat breast cancer that has spread to other parts of the body. It is used together with other cancer medicines (eg, docetaxel, trastuzumab) to treat patients with HER2-positive breast cancer. The HER2 protein is produced by some breast tumors. Pertuzumab is a monoclonal antibody that interferes with the growth of this protein, which is eventually destroyed by the body.

Pertuzumab is also used as part of a complete treatment regimen for early breast cancer before surgery and as an additional treatment for breast cancer that is at high risk for occurring again.

Pertuzumab is to be given only by or under the immediate supervision of your doctor.