Lurasidone Hydrochloride and Pyrophosphate Injection

• Generic Name: lurasidone
• Dosage Forms: n.a.
• Other Brand Names: Latuda

Acute treatment of schizophrenia in adults.

American Psychiatric Association (APA) considers most atypical antipsychotic agents first-line drugs for management of the acute phase of schizophrenia (including first psychotic episodes).

Patients who do not respond to or tolerate one drug may be successfully treated with an agent from a different class or with a different adverse effect profile.

Treatment (alone or in combination with lithium or valproate) of major depressive episodes associated with bipolar I disorder (bipolar depression).

Appears less likely to cause weight gain and to adversely affect metabolic parameters than some other atypical antipsychotic agents (e.g., olanzapine, quetiapine). Consider as alternative therapy in patients at higher risk of metabolic abnormalities (e.g., those with diabetes mellitus or hyperlipidemia).

Manufacturer states that efficacy of lurasidone in the treatment of mania associated with bipolar disorder has not been established.

• Generic Name: pyrophosphate
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Technescan PYP

• It is used with a special imaging test.