M-End PE and Naldemedine

• Generic Name: brompheniramine / codeine / phenylephrine
• Dosage Forms: n.a.
• Other Brand Names: M-End PE, Poly-Tussin AC, TL-Hist CD

Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Codeine is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

M-End PE is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

M-End PE will not treat a cough that is caused by smoking, asthma, or emphysema.

M-End PE may also be used for purposes not listed in this medication guide.

• Generic Name: naldemedine
• Dosage Forms: n.a.
• Other Brand Names: Symproic

Naldemedine reduces constipation caused by opioid pain medicine used to treat severe chronic pain.

Naldemedine is for use in adults who use opioid pain medicine to treat chronic pain that is not caused by active cancer.

Naldemedine may also be used for purposes not listed in this medication guide.