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Macrilen and Toujeo SoloStar

Determining the interaction of Macrilen and Toujeo SoloStar and the possibility of their joint administration.

Check result:
Macrilen <> Toujeo SoloStar
Relevance: 28.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Insulin glargine may affect the accuracy of the diagnostic test performed with macimorelin. It is generally recommended to discontinue insulin glargine for a washout period before administration of the test. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Drugs that directly affect the pituitary secretion of growth hormone (e.g., somatostatin, insulin, glucocorticoids, cyclooxygenase inhibitors such as aspirin and nonsteroidal anti-inflammatory drugs) and drugs that may transiently elevate growth hormone levels (e.g., clonidine, levodopa, insulin) may impact the accuracy of the macimorelin diagnostic test.

MANAGEMENT: Concomitant use of macimorelin with drugs affecting growth hormone levels should generally be avoided. A sufficient washout period following discontinuation of these drugs is recommended prior to macimorelin administration.

References
  • "Product Information. Macrilen (macimorelin)." Aeterna Zentaris, Charleston, SC.
Macrilen

Generic Name: macimorelin

Brand name: Macrilen

Synonyms: n.a.

Toujeo SoloStar

Generic Name: insulin glargine

Brand name: Toujeo SoloStar, Toujeo Max SoloStar, Basaglar KwikPen, Lantus, Lantus Solostar Pen, Lantus OptiClik Cartridge, Lantus SoloStar

Synonyms: Toujeo

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction