Magnesium gluconate and Migalastat Hydrochloride

• Generic Name: magnesium gluconate
• Dosage Forms: n.a.
• Other Brand Names: Mag-G, Magonate, Magonate Natal, Magtrate, Optimum Magnesium Gluconate

Magnesium is a naturally occurring mineral. Magnesium is important for many systems in the body, especially the muscles and nerves.

Magnesium gluconate is used as a supplement to maintain adequate magnesium in the body.

Magnesium gluconate may also be used for purposes not listed in this medication guide.

• Generic Name: migalastat
• Dosage Forms: n.a.
• Other Brand Names: Galafold

Migalastat hydrochloride is an alpha-galactosidase A (alpha-Gal A) pharmacological chaperone indicated for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene (GLA) variant based on in vitro assay data.

This indication is approved under accelerated approval based on reduction in kidney interstitial capillary cell globotriaosylceramide (KIC GL-3) substrate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.