Magnesium hydroxide and Ultracaps
Determining the interaction of Magnesium hydroxide and Ultracaps and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using magnesium hydroxide together with pancrelipase. Using these medications together may cause pancrelipase to be less effective. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Coadministration with the combination of calcium carbonate and magnesium hydroxide may reduce the therapeutic effects of pancrelipase in the treatment of steatorrhea. The mechanism involves precipitation of glycine-conjugated bile acids and formation of calcium and magnesium fatty acid soaps, resulting in a decrease in fat absorption. In addition, by increasing gastric pH, antacids may reduce the resistance of the enteric coating of some formulations of pancreatic enzymes, resulting in earlier release and destruction of enzymatic activity.
MANAGEMENT: Patients receiving pancrelipase for steatorrhea should avoid taking the medication together with a combination of calcium carbonate and magnesium hydroxide. Calcium carbonate and magnesium hydroxide may be found in certain antacids, and calcium carbonate may also be found in certain calcium or mineral supplements.
- Lankisch PG, Creutzfeldt W "Therapy of exocrine and endocrine pancreatic insufficiency." Clin Gastroenterol 13 (1984): 985-99
- "Product Information. Cotazym-S (pancrelipase)." Organon, West Orange, NJ.
- "Product Information. Cotazym (pancrelipase)." Organon, West Orange, NJ.
Generic Name: magnesium hydroxide
Brand name: Ex-Lax Milk of Magnesia, Milk of Magnesia, Pedia-Lax Chewable, Phillips Milk of Magnesia, Concentrated Phillips Milk of Magnesia, Dulcolax Milk of Magnesia
Synonyms: Magnesium Hydroxide
Generic Name: pancrelipase
Brand name: Creon, Pancreaze, Pertzye, Viokace, Zenpep, Cotazym, Viokase, Zymase, Pancrease MT 4, Pancrease MT 16, Protilase, Panase, Ku-Zyme HP, Cotazym-S, Creon 10, Creon 20, Ultrase MT 20, Protilase MT-16, Creon 5, Pancrease, Pancrease MT 10, Vio-Moore, Panokase, Ilozyme, Pancrease MT 20, Ultrase, Ultrase MT 12, Pancron D/R, Encron-10, Ultrase MT 18, Arco-Lase, Lipram, Pancrecarb MS-8, Pancrecarb MS-4, Lipram-UL 18, Lipram-CR20, Lipram-UL 12, Lipram-UL 20, Viokase 16, Pancreatil-UL 12, Pangestyme CN 10, Pangestyme CN 20, Pangestyme MT 16, Pangestyme UL 18, Pangestyme EC, Kutrase, Ku-Zyme, Lipram-CR, Plaretase, Viokase 8, Lipram-CR5, Lapase, Dygase, Pancrecarb MS-16, Pangestyme UL 20, Panocaps, Panocaps MT 16, Lipram-CR10, Palcaps 10, Lipram-PN10, Lipram-PN16, Lipram-PN20, Panokase 16, Ultresa
Synonyms: Pancrelipase
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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