Magnesium sulfate, potassium sulfate, and sodium sulfate and Theophylline Oral Solution
Determining the interaction of Magnesium sulfate, potassium sulfate, and sodium sulfate and Theophylline Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: The risk of seizures induced by the use of bowel cleansing preparations may be increased in patients on concomitant medications that can lower the seizure threshold such as selective serotonin reuptake inhibitors (SSRI antidepressants or anorectics), monoamine oxidase inhibitors, neuroleptic agents, central nervous system stimulants, opioids, tricyclic antidepressants, other tricyclic compounds (e.g., cyclobenzaprine, phenothiazines), systemic steroids, carbapenems, cholinergic agents, fluoroquinolones, interferons, chloroquine, mefloquine, lindane, and theophylline. Rare cases of generalized tonic-clonic seizures and/or loss of consciousness in association with low serum osmolality and electrolyte abnormalities (e.g., hyponatremia, hypokalemia, hypocalcemia, hypomagnesemia) have been reported with the use of bowel cleansing products in patients with no prior history of seizures. The condition resolved with correction of fluid and electrolyte abnormalities. MANAGEMENT: Caution is advised when bowel cleansing preparations are prescribed in patients treated with agents that can lower the seizure threshold. Bowel cleansing preparations should not be used if these patients have impaired renal function or perfusion, dehydration, or uncorrected electrolyte abnormalities. Baseline and postprocedure labs including serum electrolytes, calcium, phosphate, BUN, and creatinine should be considered, particularly in the elderly. Patients should be advised not to exceed the recommended dosage of their bowel cleansing preparation and to drink sufficient quantities of clear fluids before, during, and after the bowel preparation process. Administration of an electrolyte rehydration solution may help attenuate the electrolyte abnormalities and hypovolemia. References Salik JM, Kurtin P "Severe hyponatremia after colonoscopy preparation in a patient with the acquired immune deficiency syndrome." Am J Gastroenterol 80 (1985): 177-9 "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories, Braintree, MA. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 Cerner Multum, Inc. "Australian Product Information." O 0 "Product Information. Suclear (polyethylene glycol 3350 with electrolytes)." Braintree Laboratories, Braintree, MA. "Product Information. Fleet Phospho Soda (sodium biphosphate-sodium phosphate)." Fleet, CB, Lynchburg, VA. "Product Information. Visicol (sodium biphosphate-sodium phosphate)." Salix Pharmaceuticals, Raleigh, NC. View all 7 references
Professional:MONITOR: The risk of seizures induced by the use of bowel cleansing preparations may be increased in patients on concomitant medications that can lower the seizure threshold such as selective serotonin reuptake inhibitors (SSRI antidepressants or anorectics), monoamine oxidase inhibitors, neuroleptic agents, central nervous system stimulants, opioids, tricyclic antidepressants, other tricyclic compounds (e.g., cyclobenzaprine, phenothiazines), systemic steroids, carbapenems, cholinergic agents, fluoroquinolones, interferons, chloroquine, mefloquine, lindane, and theophylline. Rare cases of generalized tonic-clonic seizures and/or loss of consciousness in association with low serum osmolality and electrolyte abnormalities (e.g., hyponatremia, hypokalemia, hypocalcemia, hypomagnesemia) have been reported with the use of bowel cleansing products in patients with no prior history of seizures. The condition resolved with correction of fluid and electrolyte abnormalities.
MANAGEMENT: Caution is advised when bowel cleansing preparations are prescribed in patients treated with agents that can lower the seizure threshold. Bowel cleansing preparations should not be used if these patients have impaired renal function or perfusion, dehydration, or uncorrected electrolyte abnormalities. Baseline and postprocedure labs including serum electrolytes, calcium, phosphate, BUN, and creatinine should be considered, particularly in the elderly. Patients should be advised not to exceed the recommended dosage of their bowel cleansing preparation and to drink sufficient quantities of clear fluids before, during, and after the bowel preparation process. Administration of an electrolyte rehydration solution may help attenuate the electrolyte abnormalities and hypovolemia.
- Salik JM, Kurtin P "Severe hyponatremia after colonoscopy preparation in a patient with the acquired immune deficiency syndrome." Am J Gastroenterol 80 (1985): 177-9
- "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories, Braintree, MA.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Suclear (polyethylene glycol 3350 with electrolytes)." Braintree Laboratories, Braintree, MA.
- "Product Information. Fleet Phospho Soda (sodium biphosphate-sodium phosphate)." Fleet, CB, Lynchburg, VA.
- "Product Information. Visicol (sodium biphosphate-sodium phosphate)." Salix Pharmaceuticals, Raleigh, NC.
Generic Name: magnesium sulfate / potassium sulfate / sodium sulfate
Brand name: Suprep Bowel Prep Kit
Synonyms: Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate Oral Solution
Generic Name: theophylline
Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap
Synonyms: Theophylline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Magnesium sulfate, potassium sulfate, and sodium sulfate-Theophylline Sustained-Release Capsules
- Magnesium sulfate, potassium sulfate, and sodium sulfate-Theophylline Sustained-Release Tablets
- Magnesium sulfate, potassium sulfate, and sodium sulfate-Thera-D 2000
- Magnesium sulfate, potassium sulfate, and sodium sulfate-Thera-Gesic
- Magnesium sulfate, potassium sulfate, and sodium sulfate-Thera-Gesic Plus
- Magnesium sulfate, potassium sulfate, and sodium sulfate-Thera-Sal Topical
- Theophylline Oral Solution-Magnesium Sulfate-Sodium Chloride injection
- Theophylline Oral Solution-Magnesium Water
- Theophylline Oral Solution-Magnesium-Rougier Oral, Topical application, Route Not Applicable
- Theophylline Oral Solution-Magnevist
- Theophylline Oral Solution-Magonate (Magnesium Carbonate)
- Theophylline Oral Solution-Magonate (Magnesium Gluconate)