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Magtrate and Os-Cal 500+D

Determining the interaction of Magtrate and Os-Cal 500+D and the possibility of their joint administration.

Check result:

Magtrate <> Os-Cal 500+D

Relevance: 09.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using ergocalciferol together with magnesium gluconate can lead to elevated magnesium blood levels, particularly in individuals with reduced kidney function. Symptoms of high magnesium levels may include nausea, vomiting, flushing, drowsiness, dizziness, confusion, muscle weakness, reduced reflexes, low blood pressure, slow heart rate, and impaired breathing. You should seek medical attention if you experience these symptoms. If you are on dialysis and treated with ergocalciferol or other vitamin D medications, you should generally avoid taking products that contain magnesium without first talking to your doctor, as high levels of magnesium over time can lead to bone problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to potentially additive pharmacologic effects. Chronic hypermagnesemia may have a role in the pathogenesis of adynamic bone disease in dialysis patients.

MANAGEMENT: Patients on chronic renal dialysis treated with a vitamin D analog should avoid magnesium-containing products.

References

"Product Information. Zemplar (paricalcitol)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Hectorol (doxercalciferol)." Genzyme Corporation, Cambridge, MA.
"Product Information. One-Alpha (alfacalcidol)." Pharmel Inc, Montreal, IN.
"Product Information. Rocaltrol (calcitriol)." Roche Laboratories, Nutley, NJ.

Magtrate

Generic Name: magnesium gluconate

Brand name: Mag-G, Magtrate, Optimum Magnesium Gluconate, Magonate, Magonate Natal

Synonyms: n.a.

What is Magtrate?

Os-Cal 500+D

Generic Name: calcium / vitamin d

Brand name: Calcitrate, Caltrate 600+D, Os-Cal 500+D, Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D, UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Caltrate 600 with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P & D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Os-Cal 500+Extra D Chewable

Synonyms: n.a.

What is Os-Cal 500+D?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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