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Major Heartburn Relief Maximum Strength and Probenecid Tablets

Determining the interaction of Major Heartburn Relief Maximum Strength and Probenecid Tablets and the possibility of their joint administration.

Check result:
Major Heartburn Relief Maximum Strength <> Probenecid Tablets
Relevance: 07.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Probenecid may inhibit the tubular secretion of famotidine and thereby increase its pharmacologic effects. The clinical significance of this interaction is uncertain.

References
  • Inotsume N, Nishimura M, Nakano M, Fujiyama S, Sato T "The inhibitory effect of probenecid on renal excretion of famotidine in young, healthy volunteers." J Clin Pharmacol 30 (1990): 50-6
Major Heartburn Relief Maximum Strength

Generic Name: famotidine

Brand name: Pepcid, Heartburn Relief, Pepcid AC, Pepcid AC Maximum Strength, Pepcid AC Chewable Tablets, Pepcid Oral Suspension

Synonyms: n.a.

Probenecid Tablets

Generic Name: probenecid

Brand name: Benemid

Synonyms: Probenecid

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.