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Malarone and Panmycin

Determining the interaction of Malarone and Panmycin and the possibility of their joint administration.

Check result:
Malarone <> Panmycin
Relevance: 22.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using tetracycline together with atovaquone may decrease the effects of atovaquone. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Concomitant treatment with tetracycline has been shown to reduce atovaquone plasma concentrations by approximately 40%. The mechanism of interaction is unknown. Therapeutic failure may result.

MANAGEMENT: Clinical response to atovaquone and parasitemia should be closely monitored in patients receiving tetracycline.

References
  • "Product Information. Malarone (atovaquone-proguanil)" Glaxo Wellcome, Research Triangle Pk, NC.
Malarone

Generic Name: atovaquone / proguanil

Brand name: Malarone, Malarone Pediatric

Synonyms: n.a.

Panmycin

Generic Name: tetracycline

Brand name: Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap, Tetracon, Robitet 500, Emtet-500

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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