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Malarone Pediatric and Reglan

Determining the interaction of Malarone Pediatric and Reglan and the possibility of their joint administration.

Check result:
Malarone Pediatric <> Reglan
Relevance: 09.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using metoclopramide together with atovaquone. Using these medications together may cause atovaquone to be less effective. Contact your doctor if your condition worsens. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concomitant treatment with metoclopramide has been shown to reduce the bioavailability of atovaquone. The mechanism of interaction is unknown.

MANAGEMENT: Patients on atovaquone requiring an antiemetic should only be prescribed metoclopramide if other antiemetics are unavailable. Clinical response to atovaquone and parasitemia should be closely monitored if metoclopramide is used.

References
  • "Product Information. Malarone (atovaquone-proguanil)" Glaxo Wellcome, Research Triangle Pk, NC.
Malarone Pediatric

Generic Name: atovaquone / proguanil

Brand name: Malarone, Malarone Pediatric

Synonyms: n.a.

Reglan

Generic Name: metoclopramide

Brand name: Reglan, Metozolv ODT

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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