Mannitol Injection and Panobinostat Lactate

• Generic Name: mannitol
• Dosage Forms: injection, solution
• Other Brand Names: Osmitrol, Resectisol, Aridol

Mannitol is a diuretic that is used to reduce swelling and pressure inside the eye or around the brain.

Mannitol is also used to help your body produce more urine. mannitol is used in people with kidney failure, to remove excess water and toxins from the body.

Mannitol is sometimes given so that your body will produce enough urine to be collected and tested. This helps your doctor determine if your kidneys are working properly.

Mannitol may also be used for purposes not listed in this medication guide.

• Generic Name: panobinostat
• Dosage Forms: n.a.
• Other Brand Names: Farydak

In combination with bortezomib and dexamethasone for treatment of multiple myeloma in patients who have received ≥2 prior therapies, including bortezomib and an immunomodulatory agent (designated an orphan drug by FDA for use in this condition ).

Accelerated approval based on progression-free survival; continued approval may be contingent on verification and description of clinical benefit in confirmatory studies.