Maraviroc and Viramune (Nevirapine Tablets)
Determining the interaction of Maraviroc and Viramune (Nevirapine Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with nevirapine does not appear to significantly alter the plasma concentrations of maraviroc. In 12 study subjects, nevirapine (200 mg twice a day plus lamivudine 150 mg twice a day and tenofovir 300 mg once a day) increased the peak plasma concentration (Cmax) of a single 300 mg dose of maraviroc by 54% but did not affect the overall systemic exposure relative to historical data. No dosage adjustment of maraviroc is necessary when coadministered with nevirapine in the absence of concomitant potent CYP450 3A4 inhibitors such as itraconazole, ketoconazole, delavirdine, clarithromycin, telithromycin, nefazodone, or protease inhibitors.
- "Product Information. Selzentry (maraviroc)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
Generic Name: nevirapine
Brand name: Viramune, Viramune XR
Synonyms: Viramune
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Maraviroc-Viramune O/S
- Maraviroc-Viramune Suspension
- Maraviroc-Viramune XR
- Maraviroc-Virasal
- Maraviroc-Virasal Topical
- Maraviroc-Viravan P
- Viramune (Nevirapine Tablets)-Maraviroc Oral Solution
- Viramune (Nevirapine Tablets)-Maraviroc Tablets
- Viramune (Nevirapine Tablets)-Marcaine
- Viramune (Nevirapine Tablets)-Marcaine HCl
- Viramune (Nevirapine Tablets)-Marcaine Preservative Free
- Viramune (Nevirapine Tablets)-Marcaine Spinal