Maraviroc Oral Solution and Nexiclon XR Suspension
Determining the interaction of Maraviroc Oral Solution and Nexiclon XR Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Maraviroc and cloNIDine may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Maraviroc may potentiate the hypotensive effect of some medications. In clinical trials, symptomatic postural hypotension was observed more often with maraviroc than with placebo when administered to healthy volunteers at higher than recommended dosages. However, when given at the recommended dosage to HIV subjects, postural hypotension occurred at a rate similar to placebo (approximately 0.5%).
MANAGEMENT: Caution is advised when maraviroc is prescribed to patients on concomitant medications known to lower blood pressure. Close monitoring for development of hypotension is recommended. Ambulatory patients should be advised to avoid rising abruptly from a sitting or recumbent position and to notify their doctor if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia.
- "Product Information. Selzentry (maraviroc)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
Generic Name: maraviroc
Brand name: Selzentry
Synonyms: Maraviroc
Generic Name: clonidine
Brand name: Catapres, Catapres-TTS, Duraclon, Kapvay, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3
Synonyms: Nexiclon XR (Oral), Nexiclon XR
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Maraviroc Oral Solution-Nexium
- Maraviroc Oral Solution-Nexium (Esomeprazole Delayed-Release Capsules)
- Maraviroc Oral Solution-Nexium (Esomeprazole Powder for Suspension)
- Maraviroc Oral Solution-Nexium 24HR (Esomeprazole Delayed-Release Capsules)
- Maraviroc Oral Solution-NexIUM 24HR (Esomeprazole Delayed-Release Tablets)
- Maraviroc Oral Solution-Nexium Capsules
- Nexiclon XR Suspension-Maraviroc Tablets
- Nexiclon XR Suspension-Marcaine
- Nexiclon XR Suspension-Marcaine HCl
- Nexiclon XR Suspension-Marcaine Preservative Free
- Nexiclon XR Suspension-Marcaine Spinal
- Nexiclon XR Suspension-Marcaine/Epinephrine