Marcaine HCl and Quinidex Extentabs
Determining the interaction of Marcaine HCl and Quinidex Extentabs and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One in vitro study has suggested that quinidine may displace bupivacaine from plasma protein-binding sites. Theoretically, the risk of toxicity from the local anesthetic could increase.
- Ghoneim MM, Pandya H "Plasma protein binding of bupivacaine and its interaction with other drugs in man." Br J Anaesth 46 (1974): 435-8
Generic Name: bupivacaine
Brand name: Marcaine HCl, Marcaine Spinal, Sensorcaine, Sensorcaine-MPF, Sensorcaine-MPF Spinal, Bupivacaine Fisiopharma, Bupivacaine Spinal, Marcaine, Marcaine Preservative Free, P-Care M, ReadySharp Bupivacaine
Synonyms: n.a.
Generic Name: quinidine
Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Marcaine HCl-Quinidine
- Marcaine HCl-Quinidine Controlled-Release Tablets
- Marcaine HCl-Quinidine Extended Release Tablets
- Marcaine HCl-Quinidine Gluconate
- Marcaine HCl-Quinidine Injection
- Marcaine HCl-Quinidine Oral, Injection, Intramuscular
- Quinidex Extentabs-Marcaine Preservative Free
- Quinidex Extentabs-Marcaine Spinal
- Quinidex Extentabs-Marcaine/Epinephrine
- Quinidex Extentabs-Marcaine/Epinephrine PF
- Quinidex Extentabs-Mardrops-EX
- Quinidex Extentabs-Margesic