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Mecamylamine Hydrochloride Tablets and Poly-Vent DM (Guaifenesin, Pseudoephedrine, and Dextromethorphan Tablets and Capsules)

Determining the interaction of Mecamylamine Hydrochloride Tablets and Poly-Vent DM (Guaifenesin, Pseudoephedrine, and Dextromethorphan Tablets and Capsules) and the possibility of their joint administration.

Check result:
Mecamylamine Hydrochloride Tablets <> Poly-Vent DM (Guaifenesin, Pseudoephedrine, and Dextromethorphan Tablets and Capsules)
Relevance: 23.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using pseudoephedrine together with mecamylamine may cause an increase in blood pressure. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Limited data suggest that methyldopa and other sympatholytics may increase or prolong the pressor effect of sympathomimetics. Hypertension may result. Data exist for phenylpropanolamine and norepinephrine.

MANAGEMENT: If these drugs must be coadministered, blood pressure should be closely monitored. Discontinuation of the sympathomimetic may be necessary if hypertension develops.

References
  • McLaren EH "Severe hypertension produced by interaction of phenylpropanolamine with methyldopa and oxprenolol." Br Med J 2 (1976): 283-4
  • "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
Mecamylamine Hydrochloride Tablets

Generic Name: mecamylamine

Brand name: Inversine, Vecamyl

Synonyms: Mecamylamine

Poly-Vent DM (Guaifenesin, Pseudoephedrine, and Dextromethorphan Tablets and Capsules)

Generic Name: dextromethorphan / guaifenesin / pseudoephedrine

Brand name: Poly-Vent DM, Tusnel-DM Pediatric Drops, Aldex GS DM, Capmist DM, Desgen, Despec-DM, Maxifed DM, Anatuss DM, Ambenyl-D, Dimacol, Novahistine DMX, Ru-Tuss Expectorant, Rhinosyn-X, Sudafed Cough, Dorcol Childrens Cough, Syn-Rx DM, Guaifenex DM RX, Suda-Tussin DM, Pseudogest-DM, Robitussin Pediatric Cough and Decongestant, Benylin Multi-Symptom Cough, Sudafed Cough Syrup, Daytime Liquicap, Multi Symptom Cough and Cold, Tussin Cough and Cold, Protuss DM, Med-RX DM, Tussafed-LA, Touro CC, Balminil DM-D-E Extra Strength, Benylin DM-D-E, Benylin DM-D-E Extra Strength, Calmylin #4, Novahistine DM Expectorant with Decongestant, Medent DM, Robitussin CF, Profen Forte DM, Profen II DM, Profen II DM Liquid, S-Pak DM, Ru-Tuss DM, Dimetapp Cold and Congestion, PanMist-DM, Relacon-DM, Coldmist DM, Z-COF DM, Ambifed-G DM, Tusnel Pediatric, Touro CC-LD, Relacon-DM NR, Despec Drops, Liquicough DM, Pseudo Cough, Relasin DM, Z-Cof 12DM, Q-Tussin CF, Ambi 60/580/30, Ambi 80/780/40, Ambi 600/1000/30, Trikof-D, Pseudo DM GG, Pseudo Max DMX, SudaTex-DM, ExeFen-DMX, Medent-DMI, Donatussin DM Syrup, Ambifed DM, Tenar DM, Robitussin D, ExeClear-DM, Z-Cof 8DM, Robitussin D Cough & Cold, TL-Dex DM, Tusnel DM Pediatric Drops, Trispec PSE

Synonyms: Poly-Vent DM (Liquid)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.