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Mecamylamine Hydrochloride Tablets and Polyethylene Glycol-Electrolyte Solution and Bisacodyl

Determining the interaction of Mecamylamine Hydrochloride Tablets and Polyethylene Glycol-Electrolyte Solution and Bisacodyl and the possibility of their joint administration.

Check result:
Mecamylamine Hydrochloride Tablets <> Polyethylene Glycol-Electrolyte Solution and Bisacodyl
Relevance: 23.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using mecamylamine together with sodium bicarbonate may increase the effects of mecamylamine and lower your blood pressure or cause mental status changes. Low blood pressure can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. Talk with your doctor before using mecamylamine and sodium bicarbonate together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Alkalinization of the urine can decrease the renal elimination of mecamylamine. A more pronounced and prolonged antihypertensive action may result.

MANAGEMENT: Blood pressure should be closely monitored. It may be necessary to decrease mecamylamine dosage.

References
  • Allanby KD, Trounce JR "Excretion of mecamylamine after intravenous and oral administration." Br Med J 2 (1957): 1219-21
Mecamylamine Hydrochloride Tablets

Generic Name: mecamylamine

Brand name: Inversine, Vecamyl

Synonyms: Mecamylamine

Polyethylene Glycol-Electrolyte Solution and Bisacodyl

Generic Name: bisacodyl / polyethylene glycol 3350 / potassium chloride / sodium bicarbonate / sodium chloride

Brand name: Half Lytely and Bisacodyl Lemon Lime, HalfLytely and Bisacodyl, HalfLytely and Bisacodyl with Flavor Packs, GaviLyte-H and Bisacodyl with Flavor Packs

Synonyms: Bisacodyl and polyethylene glycol (PEG) 3350 with electrolytes

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.