Meclofenamate and Pilocarpine Hydrochloride

• Generic Name: meclofenamate
• Dosage Forms: n.a.
• Other Brand Names:

  Meclomen

Meclofenamate is a nonsteroidal anti-inflammatory drug (NSAID). Meclofenamate works by reducing hormones that cause inflammation and pain in the body.

Meclofenamate is used to treat fever or mild to moderate pain in adults. Meclofenamate is also used to relieve symptoms of osteoarthritis or rheumatoid arthritis in adults, and juvenile arthritis in children who are at least 14 years old.

Meclofenamate is also used to treat menstrual pain or heavy menstrual bleeding.

Meclofenamate is sometimes used long-term to treat symptoms of ankylosing spondylitis, gouty arthritis, or shoulder pain caused by bursitis or tendinitis.

Meclofenamate may also be used for purposes not listed in this medication guide.

• Generic Name: pilocarpine ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Pilocar, Pilopine-HS, Pilostat, Isopto Carpine, Adsorbocarpine, Pilagan with C Cap, Ocu-Carpine, Ocusert, Piloptic-1/2, Piloptic-1, Akarpine, Piloptic-2, Piloptic-3, Piloptic-4, Piloptic-6

Symptomatic treatment of radiation-induced dry mouth (xerostomia) in patients with head and neck cancer.

Symptomatic treatment of dry mouth in patients with Sjögren syndrome.

There are few comparative studies of pilocarpine and cevimeline (a similar muscarinic agonist). Although both drugs can increase salivary flow and improve symptoms of dry mouth, adverse effects may differ based on differences in selectivity and affinity for muscarinic receptors. (See Actions.)