Medihaler-Iso and Silenor

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using doxepin together with isoproterenol can affect the rhythm of your heart. Let your doctor know if you have symptoms of irregular heartbeat, chest tightness, blurred vision or nausea. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: The concomitant use of isoproterenol and tricyclic antidepressants may increase the risk of arrhythmias, especially at high doses. The mechanism has not been delineated. Tachycardia has been reported in clinical studies. Rare cases of malignant cardiac arrhythmias have also been reported in patients who took oral isoproterenol and tricyclic antidepressants; however, causality was not clearly established due to excessive doses ingested and the presence of other drugs.

MANAGEMENT: Some authorities suggest that the initial rate and dose of isoproterenol should be reduced in patients taking tricyclic antidepressants, and then titrated, as is usual according to clinical response to avoid the risk of developing hypertension or arrhythmias. Patients receiving this combination should be monitored and advised to notify their physician if they experience a fast or irregular pulse.

Medihaler-Iso

Generic Name: isoproterenol

Brand name: Isuprel

Synonyms: n.a.

What is Medihaler-Iso?

Silenor

Generic Name: doxepin

Brand name: Silenor, Sinequan, Sinequan

Synonyms: n.a.

What is Silenor?