Memantine and Donepezil Capsules and Sodium Citrate Anticoagulant Solution
Determining the interaction of Memantine and Donepezil Capsules and Sodium Citrate Anticoagulant Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The concomitant administration of memantine and drugs that alkalinize the urine may decrease the clearance of memantine, resulting in accumulation of memantine and possible increased adverse effects. Memantine clearance decreased by 80% at a urinary pH of 8. The clinical significance is unknown; however, the manufacturer recommends caution.
- "Product Information. Namenda (memantine)." Forest Pharmaceuticals, St. Louis, MO.
Generic Name: donepezil / memantine
Brand name: Namzaric, Namzaric Titration Pack
Synonyms: Donepezil and memantine, Memantine and Donepezil
Generic Name: sodium citrate
Brand name:
Synonyms: Anticoagulant Sodium Citrate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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