Memantine Hydrochloride and Trihexane

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using trihexyphenidyl together with memantine can increase the side effects of trihexyphenidyl. This can cause dryness of the mouth, large pupils, drowsiness, dizziness, difficulty urinating, constipation, nervousness, upset stomach, and decreased sweating. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSE: The concomitant use of memantine may potentiate the anticholinergic effects of trihexyphenidyl such as dry mouth, blurry vision, or urinary hesitancy. The mechanism is unknown. Clinical data have not been reported.

MANAGEMENT: Patients should be monitored for adverse effects. Dose adjustments of the anticholinergic agent may be required during coadministration.

Memantine Hydrochloride

Generic Name: memantine

Brand name: Namenda, Namenda XR

Synonyms: Memantine

What is Memantine Hydrochloride?

Trihexane

Generic Name: trihexyphenidyl

Brand name: Artane, Trihexane

Synonyms: Trihexane (Oral)

What is Trihexane?