Meperidine Hydrochloride and Panocaps

• Generic Name: meperidine
• Dosage Forms: n.a.
• Other Brand Names: Demerol, Demerol HCl, Meperitab

A strong analgesic used in the relief of moderate to severe pain.

Usually, temporary relief of moderate to severe pain such as that associated with acute and some chronic medical disorders including renal or biliary colic, acute trauma, postoperative pain, and cancer.

Used to provide analgesia during diagnostic and orthopedic procedures and during labor.

For preoperative sedation and as a supplement to anesthesia.

Use as first-line opiate therapy is discouraged because of central excitatory toxicity of metabolite (normeperidine).

Because of extensive first-pass metabolism in the liver to normeperidine, the risk of excitatory toxicity is increased with oral administration of meperidine; therefore, oral therapy is discouraged.

Has been used to relieve the pain of MI, although probably not as effective as morphine sulfate.

In symptomatic treatment of acute pain, reserve opiate analgesics for pain resulting from severe injuries, severe medical conditions, or surgical procedures, or when nonopiate alternatives for relieving pain and restoring function are expected to be ineffective or are contraindicated. Use smallest effective dosage for shortest possible duration since long-term opiate use often begins with treatment of acute pain. Optimize concomitant use of other appropriate therapies. (See Managing Opiate Therapy for Acute Pain under Dosage and Administration.)

Use for chronic pain is discouraged because of short duration of effect and risk of accumulation of normeperidine metabolite and resultant central excitatory toxicity with repeated or large doses.

Used parenterally for preoperative sedation and as a supplement to anesthesia.

Used in patients with acute pulmonary edema for its cardiovascular effects and to allay anxiety.

Do not use in the treatment of pulmonary edema resulting from a chemical respiratory irritant.

• Generic Name: pancrelipase
• Dosage Forms: n.a.
• Other Brand Names: Creon, Pancreaze, Pertzye, Ultresa, Viokace, Zenpep, Cotazym, Viokase, Zymase, Pancrease MT 4, Pancrease MT 16, Protilase, Panase, Ku-Zyme HP, Cotazym-S, Creon 10, Creon 20, Ultrase MT 20, Protilase MT-16, Creon 5, Pancrease, Pancrease MT 10, Vio-Moore, Panokase, Ilozyme, Pancrease MT 20, Ultrase, Ultrase MT 12, Pancron D/R, Encron-10, Ultrase MT 18, Arco-Lase, Lipram, Pancrecarb MS-8, Pancrecarb MS-4, Lipram-UL 18, Lipram-CR20, Lipram-UL 12, Lipram-UL 20, Viokase 16, Pancreatil-UL 12, Pangestyme CN 10, Pangestyme CN 20, Pangestyme MT 16, Pangestyme UL 18, Pangestyme EC, Kutrase, Ku-Zyme, Lipram-CR, Plaretase, Viokase 8, Lipram-CR5, Lapase, Dygase, Pancrecarb MS-16, Pangestyme UL 20, Panocaps, Panocaps MT 16, Lipram-CR10, Palcaps 10, Lipram-PN10, Lipram-PN16, Lipram-PN20, Panokase 16

Pancrelipase is used to help improve food digestion in certain conditions (eg, cystic fibrosis, pancreatitis) where the pancreas is not working properly. Pancrelipase contains the enzymes (including lipases, proteases, and amylases) needed for the digestion of proteins, starches, and fats.

This medicine is available only with your doctor's prescription.