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Metamucil (Psyllium Capsules) and Tolazamide

Determining the interaction of Metamucil (Psyllium Capsules) and Tolazamide and the possibility of their joint administration.

Check result:

Metamucil (Psyllium Capsules) <> Tolazamide

Relevance: 18.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Large doses of soluble dietary fibers such as guar gum, psyllium, or methylcellulose may add to the hypoglycemic effect of insulin and oral antidiabetic agents. Soluble fibers slow the rate of carbohydrate degradation and glucose absorption during digestion, thus they can reduce postprandial blood glucose when taken in large amounts. Soluble dietary fibers are often considered beneficial as an adjunct to insulin and oral antidiabetic agents in the management of diabetes. However, patients should be monitored for changes in diabetic medication requirements following initiation of fiber therapy.

References

Anderson JW, Allgood LD, Turner J, Oeltgen PR, Daggy BP "Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia." Am J Clin Nutr 70 (1999): 466-73
Jenkins DJ, Wolever TM, Leeds AR, et al "Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity." Br Med J 1 (1978): 1392-4
Fugh-Berman A "Herb-drug interactions." Lancet 355 (2000): 134-8

Metamucil (Psyllium Capsules)

Generic Name: psyllium

Brand name: Hydrocil, Konsyl, Laxmar, Metamucil, Natural Fiber Therapy, Reguloid, Fiberall, Syllact, Modane Bulk, V-Lax, Perdiem Fiber Powder, Konsyl-Orange, Konsyl-D, Maalox Daily Fiber Therapy, Cilium, Alramucil, Serutan, Laxative Natural, Genfiber, Fiber Eze, Konsyl for Kids, Laxmar Orange, Metamucil Orange Smooth Texture, Metamucil Orange Smooth Texture Sugar Free, Metamucil Unflavored Coarse Milled Original, Fiber Therapy, Metamucil Orange Coarse Milled Original, Metamucil Unflavored Smooth Texture, Metamucil Berry Burst Smooth Texture, Laxmar Sugar Free, Konsyl Orange Sugar-free, Metamucil Pink Lemonade Smooth Texture Sugar-Free, Metamucil Original Texture Regular, Metamucil MultiHealth Fiber, Metamucil MultiHealth Fiber Sugar-free, Reguloid Sugar Free, Reguloid Orange Smooth, Reguloid Sugar Free Orange Smooth, Konsyl Sugar Free Orange With Stevia

Synonyms: Metamucil

What is Metamucil (Psyllium Capsules)?

Tolazamide

Generic Name: tolazamide

Brand name: Tolinase

Synonyms: TOLAZamide

What is Tolazamide?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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