Methadone Injection Solution and Somavert
Determining the interaction of Methadone Injection Solution and Somavert and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Methadone may reduce the effects of pegvisomant. In clinical trials, patients on narcotic medications often required higher blood levels of pegvisomant to achieve adequate treatment response. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: In clinical trials, patients on opioids often required higher serum pegvisomant concentrations to achieve appropriate IGF-I (insulin-like growth factor-I) suppression compared with patients not receiving opioids. The mechanism of interaction is unknown.
MANAGEMENT: Clinicians should be aware of this potential interaction and adjust the dosage of pegvisomant appropriately in patients treated with opioids.
- "Product Information. Somavert (pegvisomant)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: methadone
Brand name: Dolophine, Methadose, Methadose Sugar-Free, Diskets
Synonyms: Methadone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Methadone Injection Solution-Sominex
- Methadone Injection Solution-Somnote
- Methadone Injection Solution-Sonahist
- Methadone Injection Solution-Sonahist DM
- Methadone Injection Solution-Sonata
- Methadone Injection Solution-Sonidegib
- Somavert-Methadone Oral Concentrate
- Somavert-Methadone Oral Solution
- Somavert-Methadone Powder
- Somavert-Methadone Solution
- Somavert-Methadone Tablets
- Somavert-Methadone Tablets for Oral Suspension