Methadose (Methadone Tablets for Oral Suspension) and Potassium Phosphate Tablets
Determining the interaction of Methadose (Methadone Tablets for Oral Suspension) and Potassium Phosphate Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Urinary acidifiers may increase the renal excretion of methadone. Decreased methadone levels may result. This interaction can be used to clinical advantage in cases of methadone overdose.
- Nilsson M-I, Widerlov E, Meresaar U, Anggard E "Effect of urinary pH on the disposition of methadone in man." Eur J Clin Pharmacol 22 (1982): 337-42
Generic Name: methadone
Brand name: Methadose, Dolophine, Methadose Sugar-Free, Diskets
Synonyms: Methadose (Oral Concentrate), Methadose
Generic Name: potassium acid phosphate
Brand name: K-Phos Original
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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