Methenamine Mandelate and Sporanox

• Generic Name: methenamine
• Dosage Forms: n.a.
• Other Brand Names: Hiprex, Mandelamine, Urex

Prophylaxis or suppression of recurrent UTIs (bacteriuria), especially when long-term therapy is considered necessary.

Use only after UTI has been eradicated by other appropriate anti-infectives.

Not effective in systemic bacterial infections and has no effect on bacteria in blood or tissues outside the urinary tract. Do not use alone in the treatment of acute parenchymal infections causing systemic symptoms (e.g., chills, fever).

Monitor efficacy by periodic urine cultures.

Antibacterial effects are maximal when urine pH is ≤5.5. Monitor urinary pH during therapy; use supplementary acidification, if required. Supplementary acidification may be achieved by dietary regulation and/or concomitant administration of acidifying agents (e.g., ammonium chloride, ascorbic acid, methionine). This is particularly important when the causative organisms are urea-splitting strains of Proteus or Pseudomonas which increase urinary pH.

• Generic Name: itraconazole
• Dosage Forms: oral solution
• Other Brand Names: Sporanox, Onmel, Sporanox PulsePak, Tolsura

Sporanox (itraconazole) is an antifungal medication that fights infections caused by fungus.

Sporanox is used to treat infections in adults caused by fungus, which can invade any part of the body including the lungs, mouth or throat, toenails, or fingernails.

It is not known if Sporanox is safe and effective in children.