Methenamine Mandelate and Sulfamethoxazole and Trimethoprim Tablets
Determining the interaction of Methenamine Mandelate and Sulfamethoxazole and Trimethoprim Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using methenamine together with sulfamethoxazole is not recommended. Combining these medications may cause crystals to form in the urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:CONTRAINDICATED: Some sulfonamides can form an insoluble precipitate with formaldehyde, which is generated from the hydrolysis of methenamine in acidic urine maintained by the presence of hippuric acid.
MANAGEMENT: Methenamine preparations should not be given to patients taking sulfonamides due to the risk of crystalluria. An alkalinizing agent should not be added because this may render methenamine less effective.
- "Product Information. Urised (methenamine)." Polymedica Pharmaceuticals USA Inc, Woburn, MA.
- "Product Information. Hiprex (methenamine)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Generic Name: methenamine
Brand name: Hiprex, Mandelamine, Urex
Synonyms: Methenamine
Generic Name: sulfamethoxazole / trimethoprim
Brand name: Bactrim, Bactrim DS, Bactrim IV, Septra IV, SMZ-TMP DS, Sulfatrim Pediatric, Septra, Sulfatrim, Bethaprim, Cotrim, Uroplus, Uroplus DS, Cotrim DS, Bactrim Pediatric, Bethaprim Pediatric, Sulfatrim Suspension, Cotrim Pediatric, Septra DS
Synonyms: Sulfamethoxazole and trimethoprim, Sulfamethoxazole and Trimethoprim
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Methenamine Mandelate-Sulfamethoxazole Trimethoprim Oral Suspension
- Methenamine Mandelate-Sulfamethoxazole/trimethoprim Intravenous
- Methenamine Mandelate-Sulfasalazine
- Methenamine Mandelate-Sulfasalazine Delayed-Release Tablets
- Methenamine Mandelate-Sulfasalazine Tablets
- Methenamine Mandelate-Sulfatol 10-4 Cleansing Pads
- Sulfamethoxazole and Trimethoprim Tablets-Methenamine Mandelate Tablets
- Sulfamethoxazole and Trimethoprim Tablets-Methenamine, Phenyl Salicylate, Methylene Blue, Benzoic Acid, Hyoscyamine
- Sulfamethoxazole and Trimethoprim Tablets-Methenamine, Sodium Phos Mono, Phenyl Salicylate, Methyl Blue, Hyoscyamine
- Sulfamethoxazole and Trimethoprim Tablets-Methenamine, Sodium Phosphate Monobasic, Phenyl Salicylate, Methylene Blue, and Hyoscyamine
- Sulfamethoxazole and Trimethoprim Tablets-Methergine
- Sulfamethoxazole and Trimethoprim Tablets-Methergine (Methylergonovine Injection)