Methenamine Mandelate and Zymine Liquid

• Generic Name: methenamine
• Dosage Forms: n.a.
• Other Brand Names: Hiprex, Mandelamine, Urex

Prophylaxis or suppression of recurrent UTIs (bacteriuria), especially when long-term therapy is considered necessary.

Use only after UTI has been eradicated by other appropriate anti-infectives.

Not effective in systemic bacterial infections and has no effect on bacteria in blood or tissues outside the urinary tract. Do not use alone in the treatment of acute parenchymal infections causing systemic symptoms (e.g., chills, fever).

Monitor efficacy by periodic urine cultures.

Antibacterial effects are maximal when urine pH is ≤5.5. Monitor urinary pH during therapy; use supplementary acidification, if required. Supplementary acidification may be achieved by dietary regulation and/or concomitant administration of acidifying agents (e.g., ammonium chloride, ascorbic acid, methionine). This is particularly important when the causative organisms are urea-splitting strains of Proteus or Pseudomonas which increase urinary pH.

• Generic Name: triprolidine
• Dosage Forms: n.a.
• Other Brand Names: Histex, M-Hist PD, Vanaclear PD, Vanahist PD, Zymine, Zymine XR, Tripohist, Histex Syrup, Histex PD Drops, Histex PDX

Symptomatic relief of seasonal (e.g., hay fever) or perennial (nonseasonal) allergic rhinitis or nonallergic (vasomotor) rhinitis.

Used in fixed combination with other agents (e.g., pseudoephedrine) for symptomatic relief of rhinorrhea, sneezing, oronasopharyngeal itching, lacrimation, itching eyes, and/or other symptoms (e.g., sinus congestion) associated with seasonal or perennial allergic rhinitis or nonallergic rhinitis.

Symptomatic relief of allergic conjunctivitis caused by foods or inhaled allergens.

Symptomatic treatment of mild, uncomplicated allergic skin manifestations of urticaria and angioedema.

Used in fixed combination with other agents (e.g., pseudoephedrine) for self-medication for symptomatic relief of sinus congestion and other symptoms associated with the common cold.