Methergine oral and injection and Zoledronic Acid IV

• Generic Name: methylergonovine
• Dosage Forms: tablet
• Other Brand Names: Methergine

Methergine is in a group of drugs called ergot alkaloids. It affects the smooth muscle of a woman's uterus, improving the muscle tone as well as the strength and timing of uterine contractions.

Methergine is used just after a baby is born, to help deliver the placenta (also called the "afterbirth"). It is also used to help control bleeding and to improve muscle tone in the uterus after childbirth.

Methergine may also be used for purposes not listed in this medication guide.

• Generic Name: zoledronic acid
• Dosage Forms: injection
• Other Brand Names: Reclast, Zometa, Zometa Concentrate, Aclasta

Zoledronic acid (sometimes called zoledronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Reclast and Zometa are two different brands of zoledronic acid.

Reclast is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. zoledronic acid is for use when you have a high risk of bone fracture due to osteoporosis. Reclast is also used to treat Paget's disease of bone.

Zometa is used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy). Zometa also treats multiple myeloma (a type of bone marrow cancer) or bone cancer that has spread from elsewhere in the body.

You should not use Reclast and Zometa at the same time.

Zoledronic acid may also be used for purposes not listed in this medication guide.