Methergine oral and injection and Zometa

• Generic Name: methylergonovine
• Dosage Forms: tablet
• Other Brand Names: Methergine

Methergine is in a group of drugs called ergot alkaloids. It affects the smooth muscle of a woman's uterus, improving the muscle tone as well as the strength and timing of uterine contractions.

Methergine is used just after a baby is born, to help deliver the placenta (also called the "afterbirth"). It is also used to help control bleeding and to improve muscle tone in the uterus after childbirth.

Methergine may also be used for purposes not listed in this medication guide.

• Generic Name: zoledronic acid
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Reclast, Zometa, Aclasta, Zometa Concentrate

Zometa (zoledronic acid) (sometimes called zoledronate) is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Zometa is used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy). Zometa also treats multiple myeloma (a type of bone marrow cancer) or bone cancer that has spread from elsewhere in the body.

The Reclast brand of zoledronic acid is used in men and women to treat or prevent osteoporosis caused by menopause or by taking steroids. Reclast is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.

You should not use Reclast and Zometa at the same time.