Methotrexate Sodium and Pegvaliase-pqpz Subcutaneous

• Generic Name: methotrexate
• Dosage Forms: tablet
• Other Brand Names: Otrexup, Rasuvo, Rheumatrex Dose Pack, Trexall, Xatmep, Methotrexate Sodium, Preservative Free

Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. It is also used to treat severe psoriasis and and certain forms of rheumatoid arthritis.

Methotrexate is usually given after other medications have been tried without successful treatment of symptoms.

Methotrexate made also be used for purposes not listed in this medication guide.

• Generic Name: pegvaliase
• Dosage Forms: n.a.
• Other Brand Names: Palynziq

Pegvaliase-pqpz injection is used to lower phenylalanine levels in the blood in adults with phenylketonuria (PKU), who have uncontrolled blood phenylalanine levels with their current treatment.

Pegvaliase-pqpz is available only under a restricted distribution program called Palynziq™ REMS (Risk Evaluation and Mitigation Strategy) Program.